Alexander Bjork was Hojgaard’s nearest challenger on seven-under after making seven birdies in his sparkling 64.
France’s Paul Barjon was another shot back in third, one ahead of Welshman Jamie Donaldson, England’s James Morrison, Finn Tapio Pulkkanen and home favourites Julien Brun and Martin Couvra.
Scott Hend was the best-placed Australian, after a 71. Zach Murray was two-over-par on 73, and Maverick Antcliff two shots further back on 75.
“To be fair, I don’t feel like I was that good off the tee but my approach play was very good, alongside a very good putter.” – Rasmus Hojgaard.